The biogeography of polymicrobial infection

A new Review article in Nature Reviews Microbiology, in the Microbial biofilms article series

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Jan 18, 2016
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The biogeography of polymicrobial infection

Apollo Stacy, Luke McNally, Sophie E. Darch, Sam P. Brown & Marvin Whiteley

Nature Reviews Microbiology 14, 93–105 (2016)

http://www.nature.com/nrmicro/journal/v14/n2/abs/nrmicro.2015.8.html

Abstract

Microbial communities are spatially organized in both the environment and the human body. Although patterns exhibited by these communities are described by microbial biogeography, this discipline has previously only considered large-scale, global patterns. By contrast, the fine-scale positioning of a pathogen within an infection site can greatly alter its virulence potential. In this Review, we highlight the importance of considering spatial positioning in the study of polymicrobial infections and discuss targeting biogeography as a therapeutic strategy.

Go to the profile of Magdalena Skipper

Magdalena Skipper

Executive Editor, Nature Partner Journals, Nature Publishing Group

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