Journal Highlight: Biofilm Prevention: Repelled by Holes
Prevention of biofilm formation by bacteria is of critical importance to areas that directly affect human health and life including medicine, dentistry, food processing and water treatment. In a recent study, scientists from the USA have demonstrated an effective and affordable solution for reducing attachment and biofilm formation by several pathogenic bacteria commonly associated with foodborne illnesses and medical infections.
Scientists in the USA have manufactured surfaces covered in tiny holes designed to repel the formation of bacterial biofilms. Carmen Moraru at Cornell University and Diana Borca-Tasciuc at Rensselaer Polytechnic Institute, together with co-workers from both institutes, fabricated alumina-based materials with surfaces peppered with densely packed nanoscale pores of varying sizes. The surfaces with 15-nm and 25-nm pores proved most effective in minimizing bacterial attachment and biofilm formation in trials with four pathogens, including Escherichia coli and Staphylococcus aureus. The team also discovered that the tiny pores enhanced repulsive forces, such as electrostatic force, between the material and bacteria, further limiting biofilm formation. These findings provide valuable insight into the prevention of pathogenic biofilm formation on surfaces, and are expected to have important applications in the healthcare and food industries. Read the article infull.