Prevention of Biofilm Formation and Removal of Existing Biofilms by Extracellular DNases of Campylobacter jejuni

New biofilms study published in PLoS One

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Mar 31, 2015
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The bacterium Campylobacter jejuni is a leading cause of food poisoning and in the UK there are up 80,000 confirmed cases every year. C. jejuni can form biofilms which may contribute to its transmission through the food chain.

Recently a team of researchers in the UK discovered a strain of C. jejuni called "RM1221" which has three extracellular DNase (eDNase) genes instead of just one eDNase gene in more common strains. Strain RM1221 did not form biofilms and when added to pre-formed biofilm, it resulted in the removal of the biofilm. The researchers postulate that the activity of eDNases affects C. jejuni biofilm formation.

Reference:

Brown HL, Reuter M, Hanman K, Betts RP, van Vliet AH. Prevention of Biofilm Formation and Removal of Existing Biofilms by Extracellular DNases of Campylobacter jejuni. PLoS One. 2015 Mar 24;10(3):e0121680. doi:10.1371/journal.pone.0121680. eCollection 2015. PubMed PMID: 25803828.

Sources:

http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0121680

Go to the profile of Joe Bennett

Joe Bennett

Publisher, Nature Research

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